USP22

USP22 Gene - GeneCards | UBP22 Protein | UBP22 Antibody

Complete information for USP22 gene (Protein Coding), Ubiquitin Specific Peptidase 22, including: function, proteins, disorders, pathways, orthologs, and ...

usp22

USP22 - Ubiquitin carboxyl-terminal hydrolase 22 - Homo sapiens ...

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones  ...

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USP22

5 Jan 2020 ... miR-30e-5p negatively regulates mRNA and protein levels of USP22 by binding to its specific sequence of 3'UTR to inhibit proliferation and ...

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USP22 - Wikipedia

Ubiquitin specific peptidase 22 is a protein that in humans is encoded by the USP22 gene on chromosome 17. USP22 is known to function as a histone ...

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Deubiquitinating enzyme USP22 positively regulates c-Myc stability ...

J Cell Physiol. 2019 Dec;232(12):3664-3676. doi: 10.1002/jcp.25841. Epub 2019 May 3. Deubiquitinating enzyme USP22 positively regulates c-Myc stability ...

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USP22 controls multiple signaling pathways that are essential for ...

22 Feb 2019 ... USP22, a component of the SAGA complex, is overexpressed in highly aggressive cancers, but the normal functions of this deubiquitinase are ...

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Control of CCND1 ubiquitylation by the catalytic SAGA subunit ...

17 Sep 2019 ... The deubiquitylase USP22 is frequently overexpressed in cancer and contributes to tumorigenesis by driving cell cycle progression. Current ...

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USP22 Induces Cisplatin Resistance in Lung ... - Frontiers

17 May 2019 ... USP22 Induces Cisplatin Resistance in Lung Adenocarcinoma by Regulating γH2AX-Mediated DNA Damage Repair and Ku70/Bax-Mediated ...

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ZFIN Gene: usp22

DISEASE ASSOCIATED WITH usp22 HUMAN ORTHOLOG No data available. DISEASE ASSOCIATED WITH usp22 VIA EXPERIMENTAL MODELS No data ...

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The H2B deubiquitinase Usp22 promotes antibody class switch ...

8 Mar 2019 ... To assess whether Usp22 is involved in the repair of programmed DSBs in B cells in vivo, we here generate Usp22flox/flox mice and cross ...

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OMIM Entry - * 612116 - UBIQUITIN-SPECIFIC PROTEASE 22; USP22

612116 - UBIQUITIN-SPECIFIC PROTEASE 22; USP22 - KIAA1063 - USP22.

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USP22 Regulates Oncogenic Signaling Pathways to Drive Lethal ...

1 Jan 2014 ... Increasing evidence links deregulation of the ubiquitin-specific proteases 22 ( USP22) deubitiquitylase to cancer development and progression ...

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Usp22 MGI Mouse Gene Detail - MGI:2144157 - ubiquitin specific ...

View mouse Usp22 Chr11:61151785-61175055 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression.

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Recombinant Anti-USP22 antibody [EPR18945] KO Tested ...

Knockout Tested Rabbit recombinant monoclonal USP22 antibody [EPR18945]. Validated in WB, IP, ICC/IF and tested in Mouse, Rat, Human. Cited in 2 ...

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USP22 Antagonizes p53 Transcriptional Activation by ...

25 May 2012 ... USP22 is of interest since it has been reported as one of the cancer stem cell genes that are associated with epigenetic regulation of gene ...

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USP22 deficiency leads to myeloid leukemia upon oncogenic Kras ...

USP22 deficiency in KrasG12D/+ mice resulted in shorter survival compared with control mice. This was due to a block in myeloid cell differentiation leading to ...

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USP22 Deubiquitinates CD274 to Suppress Anticancer Immunity ...

9 Sep 2019 ... USP22 Deubiquitinates CD274 to Suppress Anticancer Immunity. Xing Huang, Qi Zhang, Yu Lou, Junli Wang, Xinyu Zhao, Lin Wang, Xiaozhen ...

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Gene: Usp22 (ENSMUSG00000042506) - Summary - Mus musculus ...

Gene: Usp22 ENSMUSG00000042506 . twitter logo Twitter facebook logo Facebook email logo Email. Description. ubiquitin specific peptidase 22 [Source: MGI ...

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USP22 Antibody (C-3) | SCBT - Santa Cruz Biotechnology

USP22 Antibody (C-3) is a monoclonal USP22 antibody that detects m, r, and h USP22 by WB, IP, IF and ELISA. Cited in 1 publications.

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USP22 promotes the G1/S phase transition by upregulating FoxM1 ...

3 Jul 2014 ... USP22 promotes the G1/S phase transition by upregulating FoxM1 expression via β-catenin nuclear localization and is associated with poor ...

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E-608 | Boston Biochem

Ubiquitin carboxyl-terminal hydrolase 22 (USP22) is a specialized cysteine protease with a predicted molecular weight of 60 kDa. USP22 is a member of the  ...

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USP22 promotes hypoxia-induced hepatocellular carcinoma ...

USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation. Loading. Compose a ...

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USP22 gene symbol report | HUGO Gene Nomenclature Committee

Approved symbol. USP22. Approved name. ubiquitin specific peptidase 22. Locus type. gene with protein product. HGNC ID. HGNC:12621. Previous symbols.

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USP22 Result Summary | BioGRID

USP22. USP3L. ubiquitin specific peptidase 22. UBI. SUMO. GO Process (10). GO Function (8). GO Component (2). Gene Ontology Biological Process.

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Anti-USP22 antibody produced in rabbit Prestige Antibodies ...

Anti-USP22 antibody produced in rabbit is polyclonal, unconjugated and is suitable for immunofluorescence.

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The relationship between the expression of USP22, BMI1, and EZH2 ...

24 Nov 2019 ... In this study, we investigated the effects of the deubiquitinating enzyme USP22 on the expression of the drug-resistance genes BMI1 and EZH2 ...

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Usp22 - ubiquitin specific peptidase 22 | International Mouse ...

Gene: Usp22. Log in to follow. Name. ubiquitin specific peptidase 22. MGI ID. MGI:2144157. Synonyms. N/A. Viability. Homozygous - Lethal. View. N/A.

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Expression of USP22 in cancer - Summary - The Human Protein Atlas

Expression of USP22 (KIAA1063, USP3L) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers.

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USP22 drives colorectal cancer invasion and metastasis via ...

16 May 2019 ... https://doi.org/10.18632/oncotarget.15950 Yongmin Li, Yanmei Yang, Jingwen Li, He Liu, Fuxun Chen, Bingyang Li, Binbin Cui, Yanlong Liu.

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Gα12 ablation exacerbates liver steatosis and obesity by ... - JCI

3 Dec 2019 ... Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/ SIRT1-regulated mitochondrial respiration · Tae Hyun Kim, …

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USP22 maintains regulatory T cells by stabilizing Foxp3 protein ...

1 May 2019 ... Here, we identify USP22 as a specific deubiquitinase of Foxp3, a lineage- specifying transcription factor of regulatory T (Treg) cells. A genetic ...

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The Epigenetic Modifier Ubiquitin-specific Protease 22 (USP22 ...

16 Aug 2013 ... Results: USP22 drives differentiation of embryonic stem cells (ESCs) and represses sex-determining region Y-box 2 (SOX2) transcription.

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USP22 interacts with PALB2 and promotes chemotherapy ...

4 Nov 2019 ... USP22 interacts with PALB2 and promotes chemotherapy resistance via homologous recombination of DNA double strand breaks. Isaac K ...

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Cloning and Characterization of the Human USP22 Gene Promoter

26 Dec 2012 ... Ubiquitin-specific processing enzyme 22 (USP22) plays a direct role in regulating cell cycle, and its overexpression has been reported to be ...

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The ubiquitin hydrolase USP22 contributes to 3′-end processing of ...

8 Nov 2011 ... Here, we report that RNAi-mediated knockdown of the ubiquitin hydrolase, USP22, results in 2-fold higher ubH2B, and 2-fold lower ...

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Ubiquitin‐specific protease 22 (USP22) positively regulates RCAN1 ...

24 Dec 2014 ... Protein ubiquitination can be reversed by de‐ubiquitinating enzymes (DUBs), which are classified into two main classes, cysteine proteases ...

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USP22 down-regulation facilitates human retinoblastoma cell aging ...

Eur Rev Med Pharmacol Sci 2019; 21 (12): 2785-2792. USP22 down-regulation facilitates human retinoblastoma cell aging and apoptosis via inhibiting ...

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USP22 - ويكيبيديا

USP22‏ (Ubiquitin specific peptidase 22) هوَ بروتين يُشَفر بواسطة جين USP22 في الإنسان. محتويات. 1 الوظيفة; 2 الأهمية السريرية; 3 المراجع; 4 قراءة متعمقة ...

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Targeted eradication of gastric cancer stem cells by CD44 targeting ...

13 Dec 2019 ... Aim: USP22, a member of ubiquitin-specific proteases (USPs), is a well-defined protein that promotes poor prognosis, invasion and metastasis, ...

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USP22, an hSAGA subunit and potential cancer stem cell marker ...

Abstract: Initial studies of the mammalian hSAGA transcriptional coactivator complex identified the acetyltransferase hGCN5/PCAF as the only known...

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